9th Michaelson Symposium
Tuesday May 1, 2007
Evening
6:30 - 9:30
Welcome Reception
Renaissance Harbor Place Hotel
Wednesday May 2, 2007
Morning
Intravitreal Anti-VEGF Treatment for DME
Chair: Alain Gaudric
Moderator: Alexander J. Brucker
8:30 Spontaneous Evolution of Diabetic Macular Edema Over Three Months
Alain Gaudric
8:45 Pegaptanib Sodium (Macugen) for the Treatment of Macular Edema Following Central Retinal Vein Occlusion (CRVO)
John A. Wells
9:00 Intravitreal Injection of Pegaptanib Sodium (Macugen) versus Use of Panretinal Photocoagulation (PRP) for Proliferative Diabetic Retinopathy
Victor Gonzalez
9:15 Intravitreal Bevacizumab (Avastin) for Diabetic Macular Edema
Francesco Bandello
9:30 Update from the DRCR Network on Anti-VEGF Treatment and DME
Neil M. Bressler
9:45 Safety, Tolerability, and Bioactivity of Intravitreal VEGF Trap in Patients with Neovascular Age-related Macular Degeneration
Julia Haller
10:00 Refreshment Break
Visit Exhibits
10:30 Keynote Lecture: Ischemic Retinal Vascular Diseases and Factor X: VEGF and Beyond
Lloyd P. Aiello
Symposium: Laboratory Investigations
Chair: Einar Stefansson
Moderator: Gerard Lutty
11:00 Noninvasive Spectrophotometric Retinal Oximetry: Increased Oxygen Saturation after Laser Treatment in Human BRVO
Einar Stefansson
11:15 Characterization of Vascular Precursors in Developing Human Retina
Gerard A. Lutty
11:30 Effects of VEGF Trap on Retinal Vasculogenesis and Angiogenesis in Canine Oxygen-Induced Retinopathy (OIR)
I.A. Bhutto
11:45 Treatment or Prevention Effects of Triamcinolone Acetonide (TAAC) on Retinochoroidal Angiogenesis and Remodeling
David BenEzra
12:00 Plasmid Electrotransfer to the Ciliary Muscle: For the Sustained Intraocular Release of Therapeutic Molecules Within the Eye
Francine Behar-Cohen
Afternoon
12:15 Lunch
Visit Exhibits
Diabetic Retinopathy: Laboratory Investigation
Chair: Francesco Bandello
Moderator: Morton F. Goldberg
1:15 Proliferative Diabetic Retinopathy – Pathobiology
Benjamin Miller
1:30 Regulation of Dickkopf Protein 3 in Retinal Cells and Diabetic Retina
Yukio Sassa
1:45 PIGF-1: Its Potential Implication in the Pathogenesis of Diabetic Retinopathy
Francine Behar-Cohen
Miscellaneous Conditions
2:00 Adverse Visual Outcomes Associated with Otherwise Successful Retinal Surgery
Howard Ying
2:15 Histopathologic and Trypsin Digestion Appearance of the Retina in a 55 Year Old Woman with Incontinentia Pigmenti
Morton F. Goldberg
2:30 Susac Syndrome in Five Male Patients
Bernadette Snyers
2:45 Punctate Inner Choroidopathy: Survey Analysis of 77 Persons and New Perspective on Choroidal Neovascularization and Subretinal Fibrosis
Quan Dong Nguyen
3:00 Clinical Findings of Malattia Levatinese in Japanese
Yoshimi Nagai
3:15 Session Ends – Optional Exploratory Tour of the Inner Harbor
Thursday May 3, 2007
Morning
7:30 Michaelson Club Executive Committee Breakfast Meeting
West Room
7:30 Registration and Continental Breakfast
Visit Exhibits
Intravitreal Anti-VEGF Treatment for Neovascular AM
Chair: Ursula Schmidt-Erfurth
Moderator: Jason Slakter
8:30 Ranibizumab Monotherapy – The Current Standard?
Jason Slakter
8:50 Intravitreal bevacizumab (Avastin) for Neovascular Age-Related Macular Degeneration
Jaime Levy
9:05 Intravitreal ranibizumab (Lucentis) Injection Following Unsatisfied Results of Intravitreal bevacizumab (Avastin) Injection for Exudation
Dov Weinberger
9:20 Does Ischemia Have a Role in the Development of Choroidal Neovascularization in AMD?
Juan Grunwald
9:35 Intravitreally Injected Anti-VEGF Drugs Exert a Biological Effect in the Fellow Eye
Shlomit Schaal
9:50 Ranibizumab and bevacizumab – Pharmacokinetic and Penetration Studies
Anat Loewenstein
10:05 Is VEGF Inhibition Safe in Patients with Neovascular AMD?
Diana Do
10:20 Refreshment Break
Visit Exhibits
10:50 9th Michaelson Award Presentation and Lecture
Recipient to be announced
Moderator: David BenEzra
AMD: Risk factors and Epidemiologic Studies
Chair: Emily Chew
Moderator: Stuart L. Fine
11:20 Visual Acuity Loss Associated with Advanced AMD Fundus Lesions and with the Simplified AREDS AMD Severity Scale
Emily Chew
11:35 Incident Choroidal Neovascular Lesions in the Fellow Eyes of Participants with Unilateral Neovascular AMD During the Submacular Surgery Trials
Susan B. Bressler
11:50 Epidemiology of Age-related Maculopathy in Japan: The Hisayama Study
Tatsuro Ishibashi
Afternoon
12:15 Lunch
Visit Exhibits
Laboratory Investigation of AMD
Chair: Julia Haller
Moderator: James Handa
1:15 Evaluation of Actual versus Expected PDT Spot Size
Alexander J. Brucker
1:30 Immune-based Systemic Therapy with Copaxone for Dry Age-related Macular Degeneration (AMD)
G. Landa
1:45 Evidence for Modified Lipoproteins as a Trigger for Age-related Macular Degeneration
James T. Handa
2:00 Complement Inhibition – A New Therapeutic Approach to Macular Degeneration
Federico Grossi
Age-related Macular Degeneration and Related Diseases: Laboratory Investigations
Chair: Tatsuro Ishibashi
Moderator: Dov Weinberger
2:15 Continuous Expression of VEGF in Photoreceptors Causes Severe Choroidal Neovascularization
Yuji Oshima
2:30 Characterization of the Role of Apoptosis Inducing Factor (AIF) in Retina under Normal Conditions and Retinal Detachment
Toshio Hisatomi
3:00 Session Ends
Evening
6:30 – 10 Gala Dinner – Walters Art Gallery: From the Old World to the New World
Friday, May 4, 2007
Morning
Imaging
Chair: Bernadette Snyers
Moderator: Robert Murphy
8:30 OCT Criteria as Prognostic Factors in Antiangiogenic Therapy of Neovascular AMD
Ursula Schmidt-Erfurth
8:45 Discrepancy of Fundus Autofluorescence in Age-related Macular Degeneration between Fundus Camera and Confocal Laser Ophthalmoscope
Takeya Kohno
9:00 Pegaptanib as Maintenance Therapy in Neovascular AMD: An Interim Analysis of the LEVEL Study
Thomas R. Friberg
9:15 Neovascularization in Macular Telangiectasia – CNV or Not?
Robert P. Murphy
9:30 The Future of Imaging in Retinal Disease
Moderator: Alain Gaudric
Panelists: Ursula Schmidt-Erfurth, Juan Grunwald, Susan Bressler
10:00 Refreshment Break
Visit Exhibits
PDT – Laboratory Investigation
Chair: David BenEzra
Moderator: Benjamin Miller
10:45 Photodynamic Treatment (PDT) Using Hydrophilic or Lipophilic Photosensitizers
David BenEzra
10:30 PDT in the Monkey Eye Using a Water Soluble Bacterio-Chlorophil Derivate (WST11)
David BenEzra
Angiogenesis – Laboratory Investigations
11:00 A Novel Model for Cell Induced Ocular Neovascularization
Anat Bachar
11:15 Vascular Endothelial Growth Factor (VEGF) Polymorphisms and Their Association with Age-related Macular Degeneration
Gareth J. McKay
11:30 Effective Prevention of Angiogenesis in Ocular Systems by the Perihydroxylated Dianthraquinone-Hypericin
Tilda Barliya
11:45 Enhanced Age-related Corneal Angiogenesis in Apolipoprotein E-Deficient Mice
Shintaro Nakao
12:00 Growth Factors Enhance Neuronal Differentiation of Bone Marrow Cells in the Ischemic Retina
Nitza Goldenberg-Cohen
12:15 Closing Remarks
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